Britain’s cases rise week-on-week for seventh day in row amid spread of Indian variant

Real name: B.1.617 — now divided into B.1.617.1, B.1.617.2 and B.1.617.3

When and where was it discovered? 

The variant was first reported by the Indian government in February 2021 but the first cases appear to date back to October 2020. 

Its presence in the UK was first announced by Public Health England on April 15. There have since been at least 520 cases spotted in genetic lab testing.  

What mutations does it have? 

It has at least 13 mutations that separate it from the original Covid virus that emerged in China. The two main ones are named E484Q and L452R, although the most common version in Britain (.2) does not have E484Q.

Scientists suspect L425R can help it to transmit faster and E484Q helps it get past immune cells made in response to older variants.

There is also a mutation called T478K but researchers don’t yet know what it does.

Is it more infectious and can it evade vaccines? 

Research is ongoing but British scientists currently believe it spreads at least as fast as the Kent variant and potentially faster, but it is unlikely to slip past vaccine immunity.

SAGE advisers said in a meeting last week: ‘Early indications, including from international experience, are that this variant may be more transmissible than the B.1.1.7 [Kent] variant.’

Dr Susan Hopkins, a boss at Public Health England, said: ‘We are monitoring all of these variants extremely closely and have taken the decision to classify this as a variant of concern because the indications are that this is a more transmissible variant.’ 

Expectations are that the current Covid vaccines will still protect people against the Indian variants.

Early research by the Gupta Lab at Cambridge University found there was a small reduction in vaccine effectiveness on the original Indian variant, but it found the jabs worked better against it than they did on the South African strain. The team have not yet tested the .2 strain, which is the most common in the UK. 

A paper published by SAGE advisers recently suggested two doses of the Pfizer vaccine is good enough to protect against all known variants, and it is likely the others will provide very strong defence against severe illness, even if there is a risk of reinfection.

Professor Sharon Peacock, of PHE, claimed there was ‘limited’ evidence of E484Q’s effect on immunity and vaccines.

How deadly is it? 

Professor Peacock said: ‘There isn’t any evidence that this causes more severe disease. There’s just not enough data at the moment.’ 

Scientists say it is unlikely that the variant will be significantly more dangerous than the Kent strain. 

This is because there is no evolutionary benefit to Covid becoming more deadly. The virus’s sole goal is to spread as much as it can, so it needs people to be alive and mix with others for as long as possible to achieve this.  

Although there have been claims that the Kent variant is more deadly than the virus it replaced – the Government claimed it was around 30 per cent – there is still no conclusive evidence to show any one version of Covid is worse than another.    

Is the variant affecting children and young adults more seriously?  

Doctors in India claim there has been a sudden spike in Covid hospital admissions among people under 45, who have traditionally been less vulnerable to the disease.

There have been anecdotal reports from medics that young people make up two third of new patients in Delhi. In Bangalore, under-40s made up 58 percent of infections in early April, up from 46 percent last year.

But this could be completely circumstantial – older people are more likely to shield themselves or to have been vaccinated – and there is still no proof younger people are more badly affected by the new strain. 

The risk of children getting ill with Covid is still almost non-existent.  

Why is it a ‘variant of concern’ and should we be worried?

Public Health England listed the variant as ‘of concern’ because cases are growing rapidly and it appears to be equally infectious – or potentially even more – than other strains in Britain.

Last time a faster-spreading variant was discovered it caused chaos because the outbreak exploded and hospitals came close to breaking point in January, with almost 50,000 people dying in the second wave.

But there is currently no reason to be alarmed. Scientists believe our current vaccines will still work against the variant, preventing people from getting seriously ill or dying in huge numbers.

If it spreads faster than Kent it could make it harder to contain and make the third wave bigger, increasing the number of hospital admissions and deaths among people who don’t get vaccinated or for whom vaccines don’t work, but the jabs should take the edge off for the majority of people. 

A vaccine that can make vaccinated people very sick en masse would be a real crisis for Britain and could ’cause even greater suffering than we endured in January’, Boris Johnson warned today – but there are not yet any signs the Indian variant will be the one to do this.

How many cases have been detected in the UK?

According to data by PHE released on Friday, there are, at present, 520 confirmed cases of the B.1.617.2 variant in the UK, from 202 over the last week.

The report also showed 261 cases of B.1.617.1 and nine cases of B.1.617.3.

The cases are spread across the country, with the majority in two areas – the North West, mainly in Bolton, and London. PHE said around half of these cases are related to travel or contact with someone who has been abroad. 

Surge testing is expected to be deployed where there is evidence of community transmission.

Is B.1.617.2 variant driving the second wave in India?

India reported 412,262 new Covid-19 cases and 3,980 Covid-19-related deaths on Thursday — both new single-day records.

In the past 30 days, the country has recorded 8.3million cases.

However, it remains unclear whether the new coronavirus variants are driving the second wave.

Experts say large gatherings, and lack of preventive measures such as mask-wearing or social distancing, are playing a key role in the spread of the virus.

Although India has the world’s biggest vaccine making capacity, the country has partially or fully immunised less than 10 per cent of its 1.35billion people.